The opening credits from Deux Ex: Human Revolution are technically and conceptually fucking remarkable. How Eidos Montreal managed provide character insight along with setting the atmosphere for the game perfectly in 131 seconds is just inconceivable. There’s a whole article >here< about the creation of the cinematic interviewing both the game’s director and the director of the title sequence.
"The original concept was a descent from the macroscopic to the microscopic and from the organic to the mechanical, it was all very ambitious. We knew we’d never be able to create all the CG within the tight timeframe and limited budget, so we decided to shoot live elements to help us tell the story."- Paul Furminger, Director of the sequence.